Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.

Shipping & Handling

Shipped In

Cold Packs

Safety & Storage

Storage Temperature

Aliquot the Folate Receptor beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Safety Statement

This Folate Receptor beta antibody is available for research use only.

Regulatory & Compliance

Technical Documents

Datasheet (1)

IEfuffolate-receptor-beta-antibody-folr2-1905ct501-41-76-f54170

Specifications

CLASS

Primary Antibodies

SUBCLASS

Monoclonal

UNIPROT ID

P14207

CLONE NUMBER

1905CT501.41.76

*USAGE / SAFETY STATEMENT

This Folate Receptor beta antibody is available for research use only.

FORMAT

Purified

APPLICATION.1

WB

HOST SPECIES

Mouse

ISOTYPE

IgG2b, kappa

REACTIVITY SPECIES

Human

CLONALITY

Monoclonal (mouse origin)

PURIFICATION

Protein G purified

IMMUNOGEN

Recombinant human FOLR2 protein was used as the immunogen for the Folate Receptor beta antibody.

STORAGE BUFFER

In 1X PBS, pH 7.4, with 0.09% sodium azide

APPLICATION DETAILS

WB: 1:1000-1:2000

APPLICATION NOTES

The stated application concentrations are suggested starting points. Titration of the Folate Receptor beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.