Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. [UniProt]
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. [UniProt]
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the TLR7 antibody at -20°C.
Safety Statement
This TLR7 antibody is available for research use only.
This TLR7 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
WB
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity
IMMUNOGEN
A human recombinant partial protein was used as the immunogen for this TLR7 antibody.
STORAGE BUFFER
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
APPLICATION DETAILS
Western blot: 1:1000
APPLICATION NOTES
The stated application concentrations are suggested starting points. Titration of the TLR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the TLR7 antibody at -20°C.
Safety Statement
This TLR7 antibody is available for research use only.
Regulatory & Compliance
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