Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression.

Shipping & Handling

Shipped In

Cold Packs

Safety & Storage

Storage Temperature

Aliquot the Nkx2.5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Safety Statement

This Nkx2.5 antibody is available for research use only.

Regulatory & Compliance

Technical Documents

Datasheet (1)

TDUcvnkx2.5-antibody-f53210

Specifications

CLASS

Primary Antibodies

SUBCLASS

Polyclonal

UNIPROT ID

P42582

*USAGE / SAFETY STATEMENT

This Nkx2.5 antibody is available for research use only.

FORMAT

Antigen affinity purified

APPLICATION.1

WB, ELISA

HOST SPECIES

Rabbit

ISOTYPE

Rabbit Ig

REACTIVITY SPECIES

Mouse

CLONALITY

Polyclonal (rabbit origin)

PURIFICATION

Antigen affinity

IMMUNOGEN

This mouse Nkx2.5 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 98-133 amino acids from the Central region of the mouse protein.

STORAGE BUFFER

In 1X PBS, pH 7.4, with 0.09% sodium azide

APPLICATION DETAILS

Western blot: 1:1000-2000

APPLICATION NOTES

Titration of the Nkx2.5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.