Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity).
Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity).
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the Wdr5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This Wdr5 antibody is available for research use only.
This Wdr5 antibody is available for research use only.
FORMAT
Antigen affinity purified
APPLICATION.1
WB, ELISA
HOST SPECIES
Rabbit
ISOTYPE
Rabbit Ig
REACTIVITY SPECIES
Human, Mouse
CLONALITY
Polyclonal (rabbit origin)
PURIFICATION
Antigen affinity
IMMUNOGEN
This mouse Wdr5 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the region of mouse Wdr5.
STORAGE BUFFER
In 1X PBS, pH 7.4, with 0.09% sodium azide
REACTIVITY SPECIES (PREDICTED SPECIES)
Rat
APPLICATION DETAILS
Western blot: 1:1000
APPLICATION NOTES
Titration of the Wdr5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the Wdr5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This Wdr5 antibody is available for research use only.
Regulatory & Compliance
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We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.