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LC3A Antibody (MAP1LC3A)
SKU / CAT#: F46103-0.4ML
$37900
usd
$379.00
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  4. LC3A Antibody (MAP1LC3A)
F46103-0.4ML

LC3A Antibody (MAP1LC3A)

NSJ Bioreagents
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SKU / CAT#: F46103-0.4ML
MPN: F46103-0.4ML
$37900
usd
$379.00
Available
SHIPS May 30th
Available
SHIPS May 30th
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Description
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). MAP1A and MAP1B are microtubule-associated...
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). MAP1A and MAP1B are microtubule-associated...
Shipping & Handling
Shipped In
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Safety & Storage
Storage Temperature
Aliquot the LC3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This LC3 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
nvwOflc3-antibody-f46103
Specifications
CLASS
Primary Antibodies
SUBCLASS
Polyclonal
UNIPROT ID
Q9H492
*USAGE / SAFETY STATEMENT
This LC3 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
WB, IHC, IF, ELISA
HOST SPECIES
Rabbit
ISOTYPE
Rabbit Ig
REACTIVITY SPECIES
Human, Mouse, Rat
CLONALITY
Polyclonal (rabbit origin)
PURIFICATION
Purified
IMMUNOGEN
A portion of amino acids 1-30 from human MAP1LC3A was used as the immunogen for this LC3 antibody.
STORAGE BUFFER
In 1X PBS, pH 7.4, with 0.09% sodium azide
APPLICATION DETAILS
Western blot: 1:1000,Immunofluorescence: 1:200,IHC (Paraffin): 1:50-1:100
APPLICATION NOTES
Titration of the LC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Questions & Answers (0)
Citations (0)
Western blot analysis of LC3 antibody and rat brain lysate: Both lipidated (arrow, II) and non-lipidated (arrow, I) were detected in membrane fraction (P) but only non-lipidated LC3 was detected in soluble fraction (S).
Western blot analysis of LC3 antibody and rat brain lysate: Both lipidated (arrow, II) and non-lipidated (arrow, I) were detected in membrane fraction (P) but only non-lipidated LC3 was detected in soluble fraction (S).
Fluorescent image of Chloroquine treated U251 cells (50 uM, 16h) stained with LC3 antibody. LC3 immunoreactivity is localized to autophagic vacuoles.
+1
IHC analysis of FFPE human brain tissue stained with LC3 antibody
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the LC3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This LC3 antibody is available for research use only.
Regulatory & Compliance
Badge
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