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SensoLyte® 520 Renin Assay Kit Fluorimetric - 1 kit
Kaneka Eurogentec S.A.
SKU / CAT#: AS-72040
$68700
usd
$687.00/kit
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  4. SensoLyte® 520 Renin Assay Kit Fluorimetric - 1 kit
AS-72040

SensoLyte® 520 Renin Assay Kit Fluorimetric - 1 kit

AnaSpec Inc.
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SKU / CAT#: AS-72040
MPN: AS-72040
$68700
usd
$687.00/kit
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Available
SHIPS May 16th
Available
SHIPS May 16th
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Description
Renin, a highly specific aspartyl protease, cleaves angiotensinogen, to yield angiotensin I, which is further converted into angiotensin II by ACE (Angiotensin Converting Enzyme). Angiotensin II constricts blood vessels leading to increased blood pressure. It also increases the secretion of ADH and aldosterone, and stimulates the hypothalamus to activate the thirst reflex. Since an overactive renin-angiotensin system leads to hypertension, renin is an attractive target for the treatment of this disease. The SensoLyte® 520 Renin Assay Kit provides a convenient assay for high throughput screening...
Renin, a highly specific aspartyl protease, cleaves angiotensinogen, to yield angiotensin I, which is further converted into angiotensin II by ACE (Angiotensin Converting Enzyme). Angiotensin II constricts blood vessels leading to increased blood pressure. It also increases the secretion of ADH and aldosterone, and stimulates the hypothalamus to activate the thirst reflex. Since an overactive renin-angiotensin system leads to hypertension, renin is an attractive target for the treatment of this disease. The SensoLyte® 520 Renin Assay Kit provides a convenient assay for high throughput screening...
Shipping & Handling
Shipped In
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Safety & Storage
Storage Temperature
Store component C at -80°C. Store all other components at -20°C.  Component D can be stored at room temperature for convenience.  Protect components A and B from light and moisture.
Safety Statement
Research Use Only (RUO) - This product is exclusively intended for laboratory research purposes and shall correspond to the quality and safety standards in accordance with said research purposes. The products shall not be used by the end user for any other purposes such as (the list is not exhaustive) diagnostic, prophylactic, therapeutic, cosmetic, commercial ends, or as food, ingredients or medical devices.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
AS-72040 SensoLyte® 520 Renin Assay Kit (EN)
MSDS (1)
AS-72040 SensoLyte® 520 Renin Assay Kit  (EN)
Specifications
CLASS
Protein Assay Kits
SUBCLASS
Renin/Angiotensin (RAS) Cascade
COUNTRY OF ORIGIN
United States
APPLICATION
FRET Protease activity
UNIPROT ID
P00797
*USAGE / SAFETY STATEMENT
Research Use Only (RUO) - This product is exclusively intended for laboratory research purposes and shall correspond to the quality and safety standards in accordance with said research purposes. The products shall not be used by the end user for any other purposes such as (the list is not exhaustive) diagnostic, prophylactic, therapeutic, cosmetic, commercial ends, or as food, ingredients or medical devices.
DISCLAIMER
Labscoop LLC (the Seller), AnaSpec Inc. (the Manufacturer), and affiliates shall not be held liable for any damage resulting from handling or from contact with this product. The Seller and Manufacturer’s liability shall be limited strictly to the replacement of the non-compliant Products or Services or to the reimbursement of their price, at Seller’s sole election. The Seller and Manufacturer shall assume no other liability. Accordingly, taking account of the specific nature of the Products and Services and the multiple possible applications, the Seller and Manufacturer do not guarantee in particular that the Products and Services are adapted for the intended application, and it shall be the customer's responsibility to verify and to make sure that the Products and Services are appropriate and adequate for the intended application. Except as noted above, to the full extent permissible under the applicable legislation the Seller and Manufacturer may not be held liable for any cost or liability arising from or in connection with Products or Services, including damages or accidents to persons, damages to goods other than the Products or Services sold, loss of earnings or profits, harm to reputation, or any other prejudice arising directly or indirectly from the Products or Services, and including defective Products or Services. IN NO EVENT SHALL THE SELLER OR MANUFACTURER BE LIABLE UNDER THIS AGREEMENT FOR ANY PUNITIVE, EXEMPLARY, INDIRECT OR CONSEQUENTIAL DAMAGES, INCLUDING LOST PROFITS. The Products ordered by the Customer are exclusively intended for laboratory research purposes and shall correspond to the quality and safety standards in accordance with said research purposes. They shall not be used by the Customer for any other purposes such as (the list is not exhaustive) diagnostic, prophylactic, therapeutic, cosmetic, commercial ends, or as food, ingredients or medical devices. Without prejudice to the other provisions of this Agreement that limit or exclude the Seller and Manufacturer’s liability, no liability will be accepted if the Customer who ordered Products intended exclusively for laboratory research uses said Products for purposes other than for research.
HOST SPECIES
HEK293 (mammalian cells)
QUALITY CERTIFICATION / COMPLIANCE
Our 44,000 ft2 facility in California’s Silicon Valley, AnaSpec is a leading provider of R&D, GLP, and GMP grade proteomic products and services. Our quality is guaranteed not only through the commitment of our experienced and knowledgeable staff, but also through our highly-efficient and state-of-the-art facilities. ISO 7 Certified Cleanroom. Our state-of-the-art highly controlled GMP cleanroom area for downstream processing meets 10,000 (ISO 7) standards. Complete segregation between the upstream process (synthesis and cleavage) and the downstream processes (purification, lyophilization and packaging) mitigates the risk of cross-contamination. We have multiple cleanrooms to perform GMP peptide and dye manufacturing. AnaSpec’s GMP manufacturing is overseen by our independent QA department, that ensures GMP operations adhere to our robust Quality Management System (QMS). AnaSpec’s QA department monitors GMP manufacturing as per parts of 21 CFR 210, 211 applicable for products intended use and per part 820 of 21 CFR for Diagnostic applications. Compliant with 21 CFR parts 210, 211 & 820 & ISO13485 applicable for Product intended use
DETECTION LIMIT
0.8 ng/ml
DETECTION METHOD
Fluorescent
KIT COMPONENTS
Component A: Renin substrate 5-FAM/QXL™520 FRET peptide Ex/Em=490 nm/520 nm upon cleavage: 1.5 mM DMSO solution, 50 µL Component B: 5-FAM, fluorescence reference standard: 1mM, 20 µL Component C: Human recombinant renin: 50 µL Component D: Assay buffer: 25 mL Component E: Renin Inhibitor Ac-HPFV- (Sta)-LF-NH2: 1mM DMSO solution, 4 µL
BIOMARKER TARGET
Renin
ABSORBANCE (nm)
490
EMISSION (nm)
520
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SensoLyte® 520 Renin Assay Kit Fluorimetric - 1 kit
SensoLyte® 520 Renin Assay Kit Fluorimetric - 1 kit
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store component C at -80°C. Store all other components at -20°C.  Component D can be stored at room temperature for convenience.  Protect components A and B from light and moisture.
Safety Statement
Research Use Only (RUO) - This product is exclusively intended for laboratory research purposes and shall correspond to the quality and safety standards in accordance with said research purposes. The products shall not be used by the end user for any other purposes such as (the list is not exhaustive) diagnostic, prophylactic, therapeutic, cosmetic, commercial ends, or as food, ingredients or medical devices.
Regulatory & Compliance
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