Specifications
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
APPLICATION.1
WB, IHC,ELISA. Not yet tested in other applications. Determining optimal working dilutions by titration test.
IMMUNOGEN
Purified recombinant fragment of EphB3 (aa39-212) expressed in E. Coli.
RESEARCH AREAS
Autophagy antibody,Cancer,Cardiovascular,Cell Biology,Epigenetics & Nuclear Signaling,Developmental Biologys,Immunology,Drug Discovery Products,Metabolism,Neuroscience,Signal Transduction,Stem Cells
BACKGROUND
EphB3: EPH receptor B3. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
ALTERNAME
ETK2; HEK2; TYRO6
FORM OF ANTIBODY
Ascitic fluid containing 0.03% sodium azide.
RECOMMENDED DILUTIONS
WB:1/500 - 1/2000.IHC: 1/200 - 1/1000. ELISA: Propose dilution 1/10000.
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