Specifications
GENE ID
https://www.ncbi.nlm.nih.gov/gene/6199
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
REACTIVITY SPECIES
Human,Mouse
PURIFICATION
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
IMMUNOGEN
The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase beta around the phosphorylation site of Ser423. AA range:389-438
SPECIFICITY
Phospho-p70 S6 kinase β (S423) Polyclonal Antibody detects endogenous levels of p70 S6 kinase β protein only when phosphorylated at S423.
BACKGROUND
ribosomal protein S6 kinase B2(RPS6KB2) Homo sapiens This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015],
ALTERNAME
RPS6KB2; STK14B; Ribosomal protein S6 kinase beta-2; S6K-beta-2; S6K2; 70 kDa ribosomal protein S6 kinase 2; P70S6K2; p70-S6K 2; S6 kinase-related kinase; SRK; Serine/threonine-protein kinase 14B; p70 ribosomal S6 kinase beta; S6K-beta; p70
FORM OF ANTIBODY
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
RECOMMENDED DILUTIONS
Western Blot: 1/500 - 1/2000. <br>ELISA: 1/5000. Not yet tested in other applications.