Matuzumab biosimilar is a humanized IgG1 monoclonal antibody against human EGFR. As it only has approximately 10% murine origin it has limited immunogenicity, and being IgG1 it is capable of inducing antibody dependent cell cytotoxicity (ADCC).Matuzumab biosimilar is produced in mammalian (Chinese hamster ovary) cell culture.
Matuzumab biosimilar is a humanized IgG1 monoclonal antibody against human EGFR. As it only has approximately 10% murine origin it has limited immunogenicity, and being IgG1 it is capable of inducing antibody dependent cell cytotoxicity (ADCC).Matuzumab biosimilar is produced in mammalian (Chinese hamster ovary) cell culture.
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Safety & Storage
Storage Temperature
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Safety Statement
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
PURITY
>95% by SDS-PAGE and HPLC
CONCENTRATION
5mg/ml
HOST SPECIES
Humanized
ISOTYPE
Human IgG1
REACTIVITY SPECIES
Human
PURIFICATION
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
FORMULATION
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
SPECIFICITY
Detects human EGFR. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Matuzumab.
STORAGE BUFFER
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml
Endotoxin
≤ 0.5 EU/mg as determined by the LAL method
Target
EGFR
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Safety Statement
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Regulatory & Compliance
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