Cetuximab biosimilar is a recombinant, human/mouse chimeric monoclonal antibody that binds specifically to the extracellular domain of the human epidermal growth factor receptor (EGFR). Cetuximab biosimilar is composed of the Fv regions of a murine anti-EGFR antibody with human IgG1 heavy and kappa light chain constant regions and has an approximate molecular weight of 152 kDa. Cetuximab biosimilar is produced in mammalian (Chinese Hamster Ovary) cell culture.
Cetuximab biosimilar is a recombinant, human/mouse chimeric monoclonal antibody that binds specifically to the extracellular domain of the human epidermal growth factor receptor (EGFR). Cetuximab biosimilar is composed of the Fv regions of a murine anti-EGFR antibody with human IgG1 heavy and kappa light chain constant regions and has an approximate molecular weight of 152 kDa. Cetuximab biosimilar is produced in mammalian (Chinese Hamster Ovary) cell culture.
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Safety & Storage
Storage Temperature
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Safety Statement
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
PURITY
>95% by SDS-PAGE and HPLC
CONCENTRATION
5mg/ml
HOST SPECIES
Humanized
ISOTYPE
Human IgG1
REACTIVITY SPECIES
Human
PURIFICATION
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
FORMULATION
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
SPECIFICITY
Detects human EGFR. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Cetuximab.
STORAGE BUFFER
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml
Endotoxin
≤ 0.5 EU/mg as determined by the LAL method
Target
EGFR
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Safety Statement
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Regulatory & Compliance
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