Cyclo(Phe-Pro) is a bacterial quorum-sensing molecule that has been found in V. cholerae. It enhances ToxR-dependent transcription of leuO, a DNA binding protein, and inhibits virulence factor production in V. cholerae. Cyclo(Phe-Pro) is an inhibitor of the interaction between retinoic acid-inducible gene I (RIG-I) and the ubiquitin ligase TRIM25. It increases the viral load in Huh7 cells infected with hepatitis C virus (HCV) when used at concentrations of 1, 2.5, and 5 mM. Cyclo(Phe-Pro) (50 mg/kg) reduces the expression of IFN-β induced by poly(I:C) and increases serum HCV titers in animal models...
Cyclo(Phe-Pro) is a bacterial quorum-sensing molecule that has been found in V. cholerae. It enhances ToxR-dependent transcription of leuO, a DNA binding protein, and inhibits virulence factor production in V. cholerae. Cyclo(Phe-Pro) is an inhibitor of the interaction between retinoic acid-inducible gene I (RIG-I) and the ubiquitin ligase TRIM25. It increases the viral load in Huh7 cells infected with hepatitis C virus (HCV) when used at concentrations of 1, 2.5, and 5 mM. Cyclo(Phe-Pro) (50 mg/kg) reduces the expression of IFN-β induced by poly(I:C) and increases serum HCV titers in animal models...
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Room Temperature in continental US; may vary elsewhere
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-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
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