Obtusifolin is an anthraquinone that has been found in S. obtusifolia and has diverse biological activities. It prevents IL-1β-induced increases in NF-κB phosphorylation in chondrocytes when used at concentrations ranging from 25 to 200 µM. Oral administration of obtusifolin (100 mg/kg) reduces cartilage degradation in a mouse model of osteoarthritis induced by destabilization of the medial meniscus (DMM). Obtusifolin (30 and 90 mg/kg) reduces blood glucose levels, as well as serum malondialdehyde (MDA), nitric oxide (NO), triglyceride, and cholesterol levels, and increases serum superoxide dismutase...
Obtusifolin is an anthraquinone that has been found in S. obtusifolia and has diverse biological activities. It prevents IL-1β-induced increases in NF-κB phosphorylation in chondrocytes when used at concentrations ranging from 25 to 200 µM. Oral administration of obtusifolin (100 mg/kg) reduces cartilage degradation in a mouse model of osteoarthritis induced by destabilization of the medial meniscus (DMM). Obtusifolin (30 and 90 mg/kg) reduces blood glucose levels, as well as serum malondialdehyde (MDA), nitric oxide (NO), triglyceride, and cholesterol levels, and increases serum superoxide dismutase...
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Room Temperature in continental US; may vary elsewhere
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-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
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