EGTA is an aminopolycarboxylic acid chelating agent. It is selective for calcium over magnesium with Kapp values for calcium ranging from 6.93 to 10.7 x 105 M-1 in various buffers at pH 6.8 and 20°C. EGTA (5 mM) inhibits apoptosis induced by the sarcoplasmic/endoplasmic Ca2+-ATPase (SERCA) inhibitor thapsigargin (Item No. 10522) in isolated rat thymocytes. It has been used as an irrigation agent to remove the smear layer from the pulp canal wall on extracted human teeth. Intranasal administration of EGTA enhances adenovirus-mediated gene transfer of LacZ to the trachea and main bronchi in mice...
EGTA is an aminopolycarboxylic acid chelating agent. It is selective for calcium over magnesium with Kapp values for calcium ranging from 6.93 to 10.7 x 105 M-1 in various buffers at pH 6.8 and 20°C. EGTA (5 mM) inhibits apoptosis induced by the sarcoplasmic/endoplasmic Ca2+-ATPase (SERCA) inhibitor thapsigargin (Item No. 10522) in isolated rat thymocytes. It has been used as an irrigation agent to remove the smear layer from the pulp canal wall on extracted human teeth. Intranasal administration of EGTA enhances adenovirus-mediated gene transfer of LacZ to the trachea and main bronchi in mice...
Shipping & Handling
Shipped In
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.