Escin Ib is a triterpene saponin that has been found in A. hippocastanum and has diverse biological activities. It inhibits HIV-1 protease (IC50 = 50 µM). Escin Ib (50-200 mg/kg) inhibits carrageenan-induced paw edema in rats and scratching behavior induced by compound 48/80 (Item No. 22173) in mice. It inhibits ethanol absorption and increases glucose tolerance in rats. Escin 1b (10-50 mg/kg) also decreases mucosal lesion size and severity in a rat model of ethanol-induced gastric ulcers.
Escin Ib is a triterpene saponin that has been found in A. hippocastanum and has diverse biological activities. It inhibits HIV-1 protease (IC50 = 50 µM). Escin Ib (50-200 mg/kg) inhibits carrageenan-induced paw edema in rats and scratching behavior induced by compound 48/80 (Item No. 22173) in mice. It inhibits ethanol absorption and increases glucose tolerance in rats. Escin 1b (10-50 mg/kg) also decreases mucosal lesion size and severity in a rat model of ethanol-induced gastric ulcers.
Shipping & Handling
Shipped In
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
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We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.