Sunset-Yellow-FCF

Sunset yellow FCF is an azo dye. It displays an absorption maximum of 480 nm. It reduces LPS-induced proliferation of isolated mouse splenocytes, as well as inhibits proliferation of isolated mouse splenocytes in an allogenic mixed lymphocyte reaction when used at a concentration of 250 µg/ml. Sunset yellow FCF (0.325 mg/kg) induces chromosomal aberrations in somatic and germ cells and morphological abnormalities in sperm in mice, but it is not genotoxic in a micronucleus gut assay in mice when administered at doses up to 2,000 mg/kg. Formulations containing sunset yellow FCF have been used as...