17α-Hydroxy-progesterone
Cayman Chemical
SKU / CAT#: 33154-25G
$20800
usd
$8.32/g
33154-25G

17α-Hydroxy-progesterone

Cayman Chemical Company, Inc.
$20800
usd
$8.32/g
Available
SHIPS Jul 28th
Available
SHIPS Jul 28th
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Description
17α-Hydroxyprogesterone (17-OHP) is a steroid and precursor in the synthesis of adrenal androgens. It binds to the glucocorticoid receptor in a cell-free assay (IC50 = 82 nM for the human receptor) and induces glucocorticoid receptor transactivation in HEK293 cells (EC50 = 1.2 µM). 17-OHP (0.005-1 µM) inhibits aldosterone-induced transactivation of the mineralocorticoid receptor in cell-based assays. Serum levels of 17-OHP are increased in patients with congenital adrenal hyperplasia.
17α-Hydroxyprogesterone (17-OHP) is a steroid and precursor in the synthesis of adrenal androgens. It binds to the glucocorticoid receptor in a cell-free assay (IC50 = 82 nM for the human receptor) and induces glucocorticoid receptor transactivation in HEK293 cells (EC50 = 1.2 µM). 17-OHP (0.005-1 µM) inhibits aldosterone-induced transactivation of the mineralocorticoid receptor in cell-based assays. Serum levels of 17-OHP are increased in patients with congenital adrenal hyperplasia.
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-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
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Shipping & Handling
Shipped In
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
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