Tioxolone is an inhibitor of carbonic anhydrase I (CAI; Ki = 91 nM). It is selective for CAI over CAII, -III, -IV, -VA, -VB, -VI, -VII, -IX, -XII, and -XIV (Kis = 4,930-9,040 nM). Tioxolone is active against Gram-positive or -negative bacteria, including M. tuberculosis. It is also active against dermatophytes, yeasts, and molds.
Tioxolone is an inhibitor of carbonic anhydrase I (CAI; Ki = 91 nM). It is selective for CAI over CAII, -III, -IV, -VA, -VB, -VI, -VII, -IX, -XII, and -XIV (Kis = 4,930-9,040 nM). Tioxolone is active against Gram-positive or -negative bacteria, including M. tuberculosis. It is also active against dermatophytes, yeasts, and molds.
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.