Isovitexin is a C-glycosylated flavone that has been found in Patrinia villosa and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (IC50 = 370 µg/ml). Isovitexin (50 and 100 µg/ml) is cytotoxic to HepG2 hepatic, MCF-7 breast, and HCT116 colorectal cancer cells. It inhibits LPS-induced production of TNF-α and IL-6 and decreases inducible nitric oxide synthase (iNOS) and COX-2 levels in RAW 264.7 cells when used at a concentration of 50 µg/ml. Isovitexin (200 µg/ml) reduces cytotoxicity induced by amyloid-β (25-35)...
Isovitexin is a C-glycosylated flavone that has been found in Patrinia villosa and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (IC50 = 370 µg/ml). Isovitexin (50 and 100 µg/ml) is cytotoxic to HepG2 hepatic, MCF-7 breast, and HCT116 colorectal cancer cells. It inhibits LPS-induced production of TNF-α and IL-6 and decreases inducible nitric oxide synthase (iNOS) and COX-2 levels in RAW 264.7 cells when used at a concentration of 50 µg/ml. Isovitexin (200 µg/ml) reduces cytotoxicity induced by amyloid-β (25-35)...
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Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
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