D-Glucosamine--6-phosphate-(hydrate)

D-Glucosamine-6-phosphate (D-GlcN-6-P) is a monosaccharide intermediate of the hexosamine biosynthetic pathway. It is formed from D-fructose-6-phosphate (Item No. 19588) by glucosamine-6-phosphate synthase (GlmS) in the presence of glutamine or from D-glucosamine (Item No. 27055) by N-acetyl-D-glucosamine (GlcNAc) kinase. D-GlcN-6-P binds the GlmS riboswitch (Ki = 380 µM), a ribozyme located in the 5-UTR of the gene encoding GlmS that, when bound by D-GlcN-6-P, inhibits GlmS production and decreases D-GlcN-6-P levels. It is a precursor in the biosynthesis of uridine diphosphate-N-acetylglucosamine...