SLP7111228-(hydro-chloride)
Cayman Chemical
SKU / CAT#: 23290-25MG
$61600
usd
$24.64/mg
23290-25MG

SLP7111228-(hydro-chloride)

Cayman Chemical Company, Inc.
$61600
usd
$24.64/mg
Available
SHIPS Jul 14th
Available
SHIPS Jul 14th
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Description
SLP7111228 is a potent and selective inhibitor of sphingosine kinase (SPHK) 1 with Ki values of 0.048 and >10 μM for SPHK1 and 2, respectively. It induces a concentration-dependent decrease in sphingosine-1-phosphate (S1P; Item No. 62570) in U937 cells but has no effect on sphingosine levels. In vivo, SLP7111228 decreases blood levels of S1P in a dose-dependent manner in rats.
SLP7111228 is a potent and selective inhibitor of sphingosine kinase (SPHK) 1 with Ki values of 0.048 and >10 μM for SPHK1 and 2, respectively. It induces a concentration-dependent decrease in sphingosine-1-phosphate (S1P; Item No. 62570) in U937 cells but has no effect on sphingosine levels. In vivo, SLP7111228 decreases blood levels of S1P in a dose-dependent manner in rats.
Shipping & Handling
Shipped In
Wet ice in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
Technical Documents
Datasheet (1)
Questions & Answers (0)
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Shipping & Handling
Shipped In
Wet ice in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
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