AZ-3146
Cayman Chemical
SKU / CAT#: 19991-10MG
$15800
usd$15.80/mg
AZ-3146
Cayman Chemical Company, Inc.SKU / CAT#: 19991-10MG
MPN: 19991
$15800
usd$15.80/mg
Available
SHIPS Jul 17th
Available
SHIPS Jul 17th
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Description
AZ 3146 is an inhibitor of the monopolar spindle 1 (Mps1) checkpoint kinase (IC50 = 35 nM). It displays selectivity over 46 other kinases including Cdk1 and Aurora kinase B. It has been shown to inhibit the recruitment of Mad1, Mad2, and centromere protein E (CENP-E) to kinetochores. AZ 3146 can be used with GSK923295 (Item No. 18389), an inhibitor of CENP-E, to generate aneuploidy in cells.
AZ 3146 is an inhibitor of the monopolar spindle 1 (Mps1) checkpoint kinase (IC50 = 35 nM). It displays selectivity over 46 other kinases including Cdk1 and Aurora kinase B. It has been shown to inhibit the recruitment of Mad1, Mad2, and centromere protein E (CENP-E) to kinetochores. AZ 3146 can be used with GSK923295 (Item No. 18389), an inhibitor of CENP-E, to generate aneuploidy in cells.
Shipping & Handling
Shipped In
Room Temperature in continental US; may vary elsewhere
Hazardous
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
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Shipping & Handling
Shipped In
Room Temperature in continental US; may vary elsewhere
Hazardous
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
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