Fenofibric acid is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides. It displays high affinity for liver fatty acid binding protein (Ki = 24 nM). Fenofibric acid increases plasma apolipoprotein A-II via the response element for peroxisome proliferator-activated receptors (PPARs), although it has very low affinity for PPARs (IC50s > 100 µM for both human PPARα or PPARγ). However, in a transactivation assay, it exhibits EC50 values of 18 and 30 µM for mouse and human PPARα, respectively. Fenofibric acid, when combined with statins,...
Fenofibric acid is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides. It displays high affinity for liver fatty acid binding protein (Ki = 24 nM). Fenofibric acid increases plasma apolipoprotein A-II via the response element for peroxisome proliferator-activated receptors (PPARs), although it has very low affinity for PPARs (IC50s > 100 µM for both human PPARα or PPARγ). However, in a transactivation assay, it exhibits EC50 values of 18 and 30 µM for mouse and human PPARα, respectively. Fenofibric acid, when combined with statins,...
Shipping & Handling
Shipped In
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
4°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
4°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.