Origami Organelles™ 3-D Model Kit: CRISPR

Models are powerful tools for teaching science as they provide useful simplifications of structures and processes, helping to make the unseen seen and the complex simple. CRISPR is a revolutionary new genetic engineering technique that makes editing genomes easy and inexpensive. It is based on a type of immune system found in many types of prokaryotes. Using the kit, students first make 3-D models of the components of CRISPR—the enzyme Cas9 and guide RNAs. Next, they use these models to see how CRISPR is used to edit a genome. The models also show how CRISPR can be used to control gene transcription...