Anti-CrkL (phospho-Y207) Antibody. Rabbit polyclonal antibody to CrkL (phospho-Y207)Crk, is a transformation-specific protein that induces elevation of cellular phosphotyrosine levels, but lacks tyrosine kinase activity itself. A second protein, Nck, consists solely of three SH3 domains and one SH2 domain, while GRB2 contains an SH2 domain flanked on both sides by SH3 domains. A member of this protein class, Crk-L, is encoded by a gene located on chromosome 22, band 11, centromeric of the chronic myelogenous leukemia breakpoint region. Crk-L encodes a 303 amino acid protein with one SH2 and two...
Anti-CrkL (phospho-Y207) Antibody. Rabbit polyclonal antibody to CrkL (phospho-Y207)Crk, is a transformation-specific protein that induces elevation of cellular phosphotyrosine levels, but lacks tyrosine kinase activity itself. A second protein, Nck, consists solely of three SH3 domains and one SH2 domain, while GRB2 contains an SH2 domain flanked on both sides by SH3 domains. A member of this protein class, Crk-L, is encoded by a gene located on chromosome 22, band 11, centromeric of the chronic myelogenous leukemia breakpoint region. Crk-L encodes a 303 amino acid protein with one SH2 and two...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Refer to product data sheet for more information.
Safety Statement
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Regulatory & Compliance
Specifications
CLASS
Primary
SUBCLASS
Polyclonal
SHIPPING NOTES
Storing antibodies at various temperatures (up to 40°C) for one week does not affect their activity. As a precautionary measure, we ship all products in insulated packaging with cold packs to provide extra temperature stability in transit. The cold packs may be thawed when you receive the shipment, please be assured that this is normal and your product(s) are safe to use. Once you have received your product(s), please follow the storage instructions on the datasheet(s).
COUNTRY OF ORIGIN
China
APPLICATION
WB, IHC
TARGET ORGANS
CrkL
*USAGE / SAFETY STATEMENT
This product is for research use only. It is not intended for diagnostic or therapeutic use.
PURITY
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
PHYSICAL FORM
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
MWCO (kDa)
~ 39 kDa
HOST SPECIES
Rabbit
REACTIVITY SPECIES
Human, Mouse, Rat
CLONALITY
Polyclonal
CONJUGATION/TAG
Unconjugated
IMMUNOGEN
Synthetic phosphopeptide derived from human CrkL around the phosphorylation site of Tyrosine 207.
SPECIFICITY
p-Crk-L (Y207) pAb detects endogenous levels of Crk-L protein only when phosphorylated at Tyr207.
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Refer to product data sheet for more information.
Safety Statement
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Regulatory & Compliance
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.