Anti-CD47 Antibody [IAP/964 + B6H12.2]

Primary

Monoclonal

Storing antibodies at various temperatures (up to 40°C) for one week does not affect their activity. As a precautionary measure, we ship all products in insulated packaging with cold packs to provide extra temperature stability in transit. The cold packs may be thawed when you receive the shipment, please be assured that this is normal and your product(s) are safe to use. Once you have received your product(s), please follow the storage instructions on the datasheet(s).

Functional Studies, WB, FC, IF

IAP/964 + B6H12.2

CD47

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Liquid

200 µg/ml

Mouse

IgG1, kappa + IgG1, kappa

Human

Monoclonal

Unconjugated

Protein A/G chromatography.

WB: 1-2 µg/ml, FC: 1-2 µg / million cells, IF: 1-2 µg/ml

Clone IAP/964: Recombinant human IAP protein. Clone B6H12.2: Intact CD47 purified from placenta.

This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.