Specifications
SHIPPING NOTES
Storing antibodies at various temperatures (up to 40°C) for one week does not affect their activity. As a precautionary measure, we ship all products in insulated packaging with cold packs to provide extra temperature stability in transit. The cold packs may be thawed when you receive the shipment, please be assured that this is normal and your product(s) are safe to use. Once you have received your product(s), please follow the storage instructions on the datasheet(s).
APPLICATION
FC, WB, IF, IHC-P
*USAGE / SAFETY STATEMENT
This product is for research use only. It is not intended for diagnostic or therapeutic use.
REACTIVITY SPECIES
Human, Mouse
CONJUGATION/TAG
Unconjugated
PURIFICATION
Protein A/G chromatography.
DILUTION
FC: 1-2 µg / million cells, WB: 1-2 µg/ml, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
IMMUNOGEN
Recombinant fragment, around amino acids 1-200, of human S100A4 protein. The exact sequence is proprietary.
SPECIFICITY
S100A4 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100 genes include at least 25 members, including S100A1-S100A18, trichohyalin, filaggrin, repetin, S100P, and S100Z. S100A4 exerts its function via direct interaction with a number of proteins including P53, P63, non-muscle myosin IIA, 64 integrin, and liprin b1. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression.
STORAGE BUFFER
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.