Specifications
SHIPPING NOTES
Storing antibodies at various temperatures (up to 40°C) for one week does not affect their activity. As a precautionary measure, we ship all products in insulated packaging with cold packs to provide extra temperature stability in transit. The cold packs may be thawed when you receive the shipment, please be assured that this is normal and your product(s) are safe to use. Once you have received your product(s), please follow the storage instructions on the datasheet(s).
APPLICATION
WB, FC, IF, IHC-P
TARGET ORGANS
Cytokeratin 18
*USAGE / SAFETY STATEMENT
This product is for research use only. It is not intended for diagnostic or therapeutic use.
REACTIVITY SPECIES
Human, Canine, Feline
CONJUGATION/TAG
Unconjugated
CROSS REACTIVITY
This antibody does not cross react with Rat.
PURIFICATION
Protein A/G chromatography.
DILUTION
WB: 1-2 µg/ml, FC: 1-2 µg / million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
IMMUNOGEN
Cytoskeletal preparation extracted from the human vulvar squamous carcinoma cell line A431.
SPECIFICITY
This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
STORAGE BUFFER
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.