Anti-Smad3 (phospho-S204) Antibody. Rabbit polyclonal antibody to Smad3 (phospho-S204)Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of GFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6...
Anti-Smad3 (phospho-S204) Antibody. Rabbit polyclonal antibody to Smad3 (phospho-S204)Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of GFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Refer to product data sheet for more information.
Safety Statement
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Regulatory & Compliance
Specifications
CLASS
Primary
SUBCLASS
Polyclonal
SHIPPING NOTES
Storing antibodies at various temperatures (up to 40°C) for one week does not affect their activity. As a precautionary measure, we ship all products in insulated packaging with cold packs to provide extra temperature stability in transit. The cold packs may be thawed when you receive the shipment, please be assured that this is normal and your product(s) are safe to use. Once you have received your product(s), please follow the storage instructions on the datasheet(s).
COUNTRY OF ORIGIN
China
APPLICATION
WB
TARGET ORGANS
Smad3
*USAGE / SAFETY STATEMENT
This product is for research use only. It is not intended for diagnostic or therapeutic use.
PURITY
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 100% (by SDS-PAGE).
PHYSICAL FORM
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
MWCO (kDa)
~ 48, 55 kDa
HOST SPECIES
Rabbit
REACTIVITY SPECIES
Human, Mouse, Rat
CLONALITY
Polyclonal
CONJUGATION/TAG
Unconjugated
IMMUNOGEN
Synthetic phosphopeptide derived from human Smad3 around the phosphorylation site of Serine 204.
SPECIFICITY
p-Smad3 (S204) pAb detects endogenous levels of Smad3 protein only when phosphorylated at Ser204.
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Refer to product data sheet for more information.
Safety Statement
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Regulatory & Compliance
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