SKAP1 (Src Kinase-Associated Phosphoprotein 1, Src Family-Associated Phosphoprotein 1, Src Kinase-Associated Phosphoprotein of 55kD, SCAP1, SKAP55) (Biotin)

This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. Applications: Suitable for use in ELISA. Other applications not tested. Recommended...