PNN, ID (PNN, DRS, MEMA, Pinin, 140kD nuclear and cell adhesion-related phosphoprotein, Desmosome-associated protein, Domain-rich serine protein, Melanoma metastasis clone A protein, Nuclear protein SDK3, SR-like protein) (FITC)

Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative...