GSK690693 Hydrochloride

Small Molecules

Inhibitor

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Canada

CCN1C2=C(C(=NC=C2OC[C@H]3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N

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Non-hazardous

Non-hazardous

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

White to beige solid

≥98% (HPLC)

ISO 9001:2015

GSK690693 Hydrochloride is an ATP-competitive pan-Akt kinase inhibitor. It is derived from aminofurazan. It has shown to produce antiproliferative and apoptotic effects in tumor cell lines.

1. Heerding D.A., et al. (2008) J. Med. Chem. 51(18): 5663–5679. 2. Rhodes N., et al. (2008) Cancer Res. 68(7): 2366–2374.

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol