Specifications
SHIPPING NOTES
Blue Ice or 4ºC. All orders received in North America by 12:00 PM PST Monday to Thursday will usually be shipped out on the same day. North American customers will typically receive their orders within 1-2 business days. All shipments are F.O.B. from point of shipment, pre-paid and added to the invoice. Freight charges include but not limited to: priority service and packaging materials.Products are shipped with “cold packs” in insulated containers. There is a charge for this packaging and for the shipping costs via FedEx. Please inspect packages immediately upon receipt and inform Labscoop Customer Support of any shortage or damage within 48 hours of receipt. We can only accept returns after we have given prior authorization and issued specific shipping instructions. If a customer wishes to use their own FedEx account number please indicate this on the purchase order or during checkout.
APPLICATION
WB, IHC, ICC/IF, IP, ELISA
GENE ID
https://www.ncbi.nlm.nih.gov/gene/7314
*USAGE / SAFETY STATEMENT
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
ANTIBODY TYPE
WB (1:10000); optimal dilutions for assays should be determined by the user.
REACTIVITY SPECIES
Species Independent
CONJUGATION/TAG
Unconjugated
PURIFICATION
Protein A Purified
QUALITY CERTIFICATION / COMPLIANCE
ISO 9001:2015
IMMUNOGEN
Ubiquitin conjugated lysozyme
SPECIFICITY
Detects ubiquitinated proteins and ubiquitin chains. Does not detect free ubiquitin.
STORAGE BUFFER
10mM phosphate buffer, 0.15M NaCl pH7.4, 0.1% sodium azide *Storage buffer may change when conjugated
ANTIBODY ID
https://antibodyregistry.org/search.php?q=AB_2699358
CELLUAR LOCALIZATIONS
Cytoplasm | Nucleus
SCIENTIFIC BACKGROUND
Ubiquitin is a small protein found ubiquitously in all tissue types and acts as a post translational modification. It can bind to its substrate either as a single ubiquitin molecule or in a chain. It is involved in many regulatory processes, which include proteasomal degradation, signal transduction, DNA repair, endocytosis and autophagy.
REFERENCES
1. Chen J., & Chen Z. (2013). Curr Opin Immunol. (1): 4-12.
2. Shaid S., Brandts C., Serve H., & Dikic I. (2013). Cell Death Differ. 20(1): 21-30.
RESEARCH AREA
Cell Signaling | Post-translational Modifications | Ubiquitination | Neuroscience | Neurodegeneration | Alzheimer's Disease
ALTERNATIVE NAMES
Polyubiquitin B Antibody, RPS27A Antibody, UBA52 Antibody, UBB Antibody, UBC Antibody, ubiquitin B Antibody