Oct-1, Rat, Control Peptide (Organic Cation Transporter 1)

Control peptide for O5400-06 (affinity purified antibody) and O5400-07 (antiserum). Mammalian kidney and liver are critical in maintaining physiological ionic environment. Kidney specializes in removing toxins, drugs, and other organic cations from the blood by an active process called "renal secretion". Functional studies have identified two distinct categories of organic cation transporters (Octs): a system driven by transmembrane potential difference that governs the influx of cations, whereas the H+-gradient-dependent transport system may mediate the efflux of organic cations. Several multispecific,...