EBF3 (Early B-cell factor 3) belongs to the conserved Olf/EBF family of helix-loop-helix transcription factors, which regulate neurogenesis and differentiation. It recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. EBF3 is expressed in normal brain but is silenced in brain tumors suggesting that it may regulate a transcriptional program underlying a putative tumor suppression pathway.
Applications:
Suitable for use in ELISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested.
Recommended Dilution:
Optimal dilutions to be determined by the...
EBF3 (Early B-cell factor 3) belongs to the conserved Olf/EBF family of helix-loop-helix transcription factors, which regulate neurogenesis and differentiation. It recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. EBF3 is expressed in normal brain but is silenced in brain tumors suggesting that it may regulate a transcriptional program underlying a putative tumor suppression pathway.
Applications:
Suitable for use in ELISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested.
Recommended Dilution:
Optimal dilutions to be determined by the...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Monoclonal Antibodies
SUBCLASS
Transcription Factors
APPLICATION
E IHC WB
CLONE NUMBER
8D6
ACCESSION#
NP_001005463
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified.
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
GRADE
Purified
ANTIBODY TYPE
Mab
HOST SPECIES
human
ISOTYPE
IgG1,k
CROSS REACTIVITY
Hu Mo
IMMUNOGEN
EBF3 (NP_001005463, 381-481aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
SPECIFIC ACTIVITY
Recognizes human EBF3. Species Crossreactivity: mouse.
COMMODITY CODE
30021010
HOST
mouse
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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