ETV7 (ETS Related Protein Tel2, Ets Transcription Factor TEL-2b, Ets Transcription Factor TEL2, ETS Translocation Variant 7, ets Variant 7, ets Variant Gene 7 (TEL2 OncoGene), ets Variant Gene 7, ETS-Related Protein Tel2, ETV7, ETV7_HUMAN, TEL 2, Tel Related Ets Factor, Tel-Related Ets Factor, TEL2, TEL2 OncoGene, TELB, Transcription Factor ETV7, Transcription Factor Tel 2, Transcription Factor Tel-2, TREF,)

Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. Members of the Ets gene family exhibit varied patterns of tissue expression and share a highly conserved carboxy terminal domain which contains a sequence related to the SV40 large T antigen nuclear localization sequence. This conserved carboxy domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. TEL2, also known as ETV7 (ets variant gene 7), TREF or...