CYP2D6 (Debrisoquine 4-hydroxylase, Cytochrome P450-DB1, CYPIID6, Cytochrome P450 2D6, CYP2DL1) (PE)

CYP2D6 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended...