Chromogranin A (CGA, CHG A, Pancreastatin, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, Vasostatin, SPI) (Biotin)

The prohormone chromogranin A (CgA) is a member of the chromogranin:secretogranin protein family of regulated secretory proteins, which are widely distributed in secretory granules of endocrine, neuroendocrine, and neuronal cells. It is required for the formation of dense-core secretory granules and hormone sequestration in sympathoadrenal chromaffin cells. It functions as prohormones, giving rise to bioactive peptides, vasostatin, pancreastatin, and parastatin as a result of post-translational proteolytic processing. Peptides derived from chromogranin A have autocrine, paracrine, and endocrine...