This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Applications:
Suitable for use in Western Blot and Immunofluorescence. Other applications have not been tested.
Recommended Dilution:
Western Blot: 1:1000
Immunofluorescence: 1:10-1:50
Optimal dilutions...
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Applications:
Suitable for use in Western Blot and Immunofluorescence. Other applications have not been tested.
Recommended Dilution:
Western Blot: 1:1000
Immunofluorescence: 1:10-1:50
Optimal dilutions...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
Topoisomerases
APPLICATION
IF WB
ACCESSION#
NP_003277.1
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by Protein A affinity chromatography.
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
GRADE
Affinity Purified
ANTIBODY TYPE
Pab
HOST SPECIES
human
ISOTYPE
IgG
CROSS REACTIVITY
Hu
IMMUNOGEN
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids aa 2-31 in the N-terminal region of human TOP1, UniProt Accession #NP_003277.1;P11387
Species sequence homology: hamster, mouse, rat
SPECIFIC ACTIVITY
Recognizes human TOP1.
SWISS PROT#
P11387
COMMODITY CODE
30021010
HOST
rabbit
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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